Best bank: Fifth Third Bank
Fifth Third’s acquisition of Comerica is a transformative move for the bank. News of the deal was also one of the most important moments in US banking in 2025, creating the industry’s ninth-largest bank by assets.
Fifth Third grabbed an important opportunity in Comerica but it is far from reliant on M&A for growth. It opened 50 new branches in the fast-growing southeastern market in 2025, including its 200th branch in Florida, 100th branch in the Carolinas, and its first branch in Alabama.
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